Five people belonging to a marriage party were killed on Tuesday morning when the car they were travelling in, collided head on with a truck coming from the opposite direction.
The incident took place in the Jalalpur police circle on the Varanasi-Lucknow national highway.
Chief Minister Yogi Adityanath has expressed grief over the incident.
The deceased were returning from a wedding ceremony in Varanasi when the car driver apparently fell asleep. One person was seriously injured in the mishap.
The car turned into a mangled heap of metal and gas cutters had to be used to bring out the bodies.
A police spokesman said that the bodies, all from one family, have been sent for post mortem and further investigations are underway.